H-Gly-Gly-Val-D-Cys(1)-Pro-Lys-Ile-Leu-Lys-Lys-Cys(2)-Arg-Arg-Asp-Ser-Asp-Cys(3)-Pro-Gly-Ala-D-Cys(1)-Ile-Cys(2)-Arg-Gly-Asn-Gly-Tyr-D-Cys(3)-Gly-Ser-Gly-Ser-Asp-OH

InChIKey	`IWNWXPRWSFWNMU-GYSAZADJSA-N`
Compound Name	H-Gly-Gly-Val-D-Cys(1)-Pro-Lys-Ile-Leu-Lys-Lys-Cys(2)-Arg-Arg-Asp-Ser-Asp-Cys(3)-Pro-Gly-Ala-D-Cys(1)-Ile-Cys(2)-Arg-Gly-Asn-Gly-Tyr-D-Cys(3)-Gly-Ser-Gly-Ser-Asp-OH
Canonical SMILES	CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)CN)C(C)C)CSSC[C@H]2NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H]3CSSC[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC1=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N3)NC(=O)[C@H]([C@@H](C)CC)NC2=O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Homologous
Avg pChEMBL	8.61
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P07477	PRSS1	Homo sapiens	Human	PF00089	9.8	Ki	ChEMBL;BindingDB
P07478	PRSS2	Homo sapiens	Human	PF00089	9.8	Ki	ChEMBL
P35030	PRSS3	Homo sapiens	Human	PF00089	9.8	Ki	ChEMBL
P00747	PLG	Homo sapiens	Human	PF00051 PF00024 PF00089	7.5	Ki	ChEMBL;BindingDB
P00748	F12	Homo sapiens	Human	PF00008 PF00039 PF00040 PF00051 PF00089	6.1	Ki	ChEMBL;BindingDB