Molecule Details
InChIKeyIVSCKYBGQGPVDS-VAWYXSNFSA-N
Compound Name(E)-N-hydroxy-3-[3-[[[1-(3,4,5-trimethoxyphenyl)-9H-pyrido[3,4-b]indol-3-yl]amino]methyl]phenyl]prop-2-enamide
Canonical SMILESCOc1cc(-c2nc(NCc3cccc(/C=C/C(=O)NO)c3)cc3c2[nH]c2ccccc23)cc(OC)c1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.08
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13547 HDAC1 Homo sapiens Human PF00850 8.9 IC50 ChEMBL;BindingDB
Q9UBN7 HDAC6 Homo sapiens Human PF00850 PF02148 8.5 IC50 ChEMBL;BindingDB
O15379 HDAC3 Homo sapiens Human PF00850 6.8 IC50 ChEMBL;BindingDB