Molecule Details
InChIKeyIUWWRSQCDUQDEZ-CAQPCFEESA-N
Canonical SMILESC[C@@H](Oc1cc(C(=O)N(C)C)ccc1Nc1nc(O[C@H]2CC[C@@](C)(O)CC2)c2c(Cl)c[nH]c2n1)C(F)(F)F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL9.65
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P45983 MAPK8 Homo sapiens Human PF00069 10.5 IC50 ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 10.2 IC50 ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 10.0 IC50 ChEMBL
P53779 MAPK10 Homo sapiens Human PF00069 10.0 IC50 ChEMBL
Q9BXA7 TSSK1B Homo sapiens Human PF00069 9.7 IC50 ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 9.6 IC50 ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 9.2 IC50 ChEMBL
P33981 TTK Homo sapiens Human PF00069 8.0 IC50 ChEMBL