InChIKey	IUBSYMUCCVWXPE-UHFFFAOYSA-N
Compound Name	Metoprolol
Canonical SMILES	COCCc1ccc(OCC(O)CNC(C)C)cc1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.07
Source	ChEMBL;BindingDB

DrugBank ID	DB00264
Drug Name	Metoprolol
CAS Number	51384-51-1
Groups	approved investigational
ATC Codes	C07FB02 C07FX05 C07FX03 C07FB13 C07AB02 C07BB52 C07CB02 C07BB02
Description	Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavail...

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Categories: Adrenergic Agents Adrenergic Antagonists Adrenergic beta-1 Receptor Antagonists Adrenergic beta-Antagonists Agents causing hyperkalemia Alcohols Amines Amino Alcohols Antiarrhythmic agents Antihypertensive Agents Antihypertensive Agents Indicated for Hypertension Beta Blocking Agents and Thiazides Beta Blocking Agents, Selective Beta Blocking Agents, Selective, and Thiazides Beta blocking agents and calcium channel blockers Beta-Blockers (Beta1 Selective) Bradycardia-Causing Agents Cardiovascular Agents Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (moderate) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A4 Substrates (strength unknown) Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Drugs causing inadvertant photosensitivity Drugs that are Mainly Renally Excreted Hypotensive Agents OCT2 Inhibitors Photosensitizing Agents Propanolamines

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Cross-references: BindingDB: 25756 ChEBI: 6904 CHEMBL13 ChemSpider: 4027 Drugs Product Database (DPD): 2167 Guide to Pharmacology: 553 IUPHAR: 553 C07202 D02358 PharmGKB: PA450480 PubChem:4171 PubChem:46506211 RxCUI: 6918 Therapeutic Targets Database: DAP000481 Wikipedia: Metoprolol