(1R,2S,3R,5S)-3-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-(2-aminoquinolin-7-yl)ethyl]cyclopentane-1,2-diol

InChIKey	`IUBFXROFEOCTGQ-GVXRKXQCSA-N`
Compound Name	(1R,2S,3R,5S)-3-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-(2-aminoquinolin-7-yl)ethyl]cyclopentane-1,2-diol
Canonical SMILES	`Nc1ccc2ccc(CC[C@H]3C[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.77
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O14744	PRMT5	Homo sapiens	Human	PF05185 PF17286 PF17285	9.7	IC50	ChEMBL;BindingDB
Q9BQA1	WDR77	Homo sapiens	Human	PF00400	9.6	IC50	ChEMBL
Q86U44	METTL3	Homo sapiens	Human	PF05063	7.0	IC50	ChEMBL