Molecule Details
| InChIKey | ITJNARMNRKSWTA-UHFFFAOYSA-N |
|---|---|
| Compound Name | Nisoxetine |
| Canonical SMILES | CNCCC(Oc1ccccc1OC)c1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.25 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB09186 |
|---|---|
| Drug Name | Nisoxetine |
| CAS Number | 53179-07-0 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Nisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s. It was originally investigated as an antidepressant but has no current clinical applications aside from being a research standard SNRI. It has been used to research obesity and energy balance, and exerts some ... |
Categories: Adrenergic Uptake Inhibitors Amines Antidepressive Agents Central Nervous System Depressants Norepinephrine, antagonists & inhibitors Propylamines
Cross-references: BindingDB: 22417 ChEBI: 73410 CHEMBL295467 ChemSpider: 4344 D05173 PubChem:4500 PubChem:310265094 Wikipedia: Nisoxetine