[4-[6-(4-Piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinolin-8-yl]methanamine

InChIKey	`ISWRGOFCPBCOGR-UHFFFAOYSA-N`
Compound Name	[4-[6-(4-Piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinolin-8-yl]methanamine
Canonical SMILES	`NCc1cccc2c(-c3cnn4cc(-c5ccc(N6CCNCC6)cc5)cnc34)ccnc12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.19
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q04771	ACVR1	Homo sapiens	Human	PF01064 PF07714 PF08515	6.3	IC50	ChEMBL;BindingDB
O00238	BMPR1B	Homo sapiens	Human	PF01064 PF07714 PF08515	6.2	IC50	ChEMBL;BindingDB
P37023	ACVRL1	Homo sapiens	Human	PF07714 PF08515	6.0	IC50	ChEMBL;BindingDB