Molecule Details
| InChIKey | ISBHYKVAFKTATD-SNVBAGLBSA-N |
|---|---|
| Compound Name | Adriforant |
| Canonical SMILES | CN[C@@H]1CCN(c2cc(NCC3CC3)nc(N)n2)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.67 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB15027 |
|---|---|
| Drug Name | Adriforant |
| CAS Number | 943057-12-3 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Adriforant is under investigation in clinical trial NCT00992342 (A Phase 1 Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03893787 In Healthy Adult Volunteers). |
Cross-references: BindingDB: 50356884 CHEMBL1915540 ChemSpider: 28480349 ZINC: ZINC000073196039
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| Q9H3N8 | HRH4 | Histamine H4 receptor | antagonist | targets |