Molecule Details
| InChIKey | IRNVMUQZQDLZAK-UHFFFAOYSA-N |
|---|---|
| Compound Name | Pyrazine-Pyridine Biheteroaryl 56 |
| Canonical SMILES | Clc1cccc(Nc2cncc(-c3cncc(NCCCc4cccnc4)c3)n2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.54 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P35968 | KDR | Homo sapiens | Human | PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 | 7.1 | IC50 | ChEMBL |
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 6.5 | IC50 | BindingDB |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 6.5 | IC50 | ChEMBL |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 6.5 | IC50 | ChEMBL |
| P09619 | PDGFRB | Homo sapiens | Human | PF00047 PF13927 PF25305 PF07714 | 6.1 | IC50 | BindingDB |