Molecule Details
InChIKeyIRIRASPSMMWZOM-CJRSTVEYSA-N
Canonical SMILESOC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)c(F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL8.91
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21603
Drug NameNizubaglustat
CAS Number1633666-49-5
Groups investigational
ATC Codes nan
DescriptionNizubaglustat is a small molecule drug. The usage of the INN stem '-glustat' in the name indicates that Nizubaglustat is a ceramide glucosyltransferase inhibitor. Nizubaglustat is under investigation in clinical trial NCT07054515 (A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ...

Cross-references: BindingDB: 50028257 CHEMBL3354637 ZINC: ZINC000299830626
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HCG7 GBA2 Homo sapiens Human PF04685 PF12215 9.2 IC50 ChEMBL;BindingDB
Q16739 UGCG Homo sapiens Human PF13506 8.6 IC50 ChEMBL;BindingDB