(2R,3R,4S)-5-Fluoro-3-(4-hydroxy-phenyl)-4-methyl-2-{4-[(S)-2-((R)-2-methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-chroman-6-ol

InChIKey	`IQWWKHVNEDNTHC-FSQCKCQLSA-N`
Compound Name	(2R,3R,4S)-5-Fluoro-3-(4-hydroxy-phenyl)-4-methyl-2-{4-[(S)-2-((R)-2-methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-chroman-6-ol
Canonical SMILES	`C[C@@H]1c2c(ccc(O)c2F)O[C@@H](c2ccc(OC[C@H](C)N3CCC[C@H]3C)cc2)[C@H]1c1ccc(O)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	9.46
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	10.2	pIC50	TTD_MultiTarget
P03372	ESR1	Homo sapiens	Human	PF12743 PF00104 PF02159 PF00105	9.2	IC50	ChEMBL;BindingDB
Q92731	ESR2	Homo sapiens	Human	PF12497 PF00104 PF00105	8.4	IC50	ChEMBL;BindingDB
Q96WX4	erg6	Pneumocystis carinii (strain B80)	Pathogen	PF08241 PF08498	10.2	pIC50	TTD_MultiTarget