Molecule Details
InChIKeyIQIKXZMPPBEWAD-CQSZACIVSA-N
Compound NameSuvecaltamide
Canonical SMILESCC(C)c1ccc(CC(=O)N[C@H](C)c2ccc(OCC(F)(F)F)cn2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.61
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB19139
Drug NameSuvecaltamide
CAS Number953778-58-0
Groups investigational
ATC Codes nan
DescriptionSuvecaltamide is under investigation in clinical trial NCT05122650 (A Study to Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)).

Cross-references: BindingDB: 50192668 CHEMBL1684950 ChemSpider: 26388955
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
O43497 CACNA1G Homo sapiens Human PF00520 8.9 IC50 ChEMBL;BindingDB
Q9P0X4 CACNA1I Homo sapiens Human PF00520 8.8 IC50 ChEMBL;BindingDB
O95180 CACNA1H Homo sapiens Human PF00520 8.1 IC50 ChEMBL;BindingDB