Target not found.
Molecule Details
InChIKeyIQFZADSTVFSHDX-UHFFFAOYSA-N
Canonical SMILESO=c1[nH]ncc(N2CCc3c(ncnc3Oc3ccc(F)cc3C(F)(F)F)C2)c1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.92
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21510
Drug NameEvifacotrep
CAS Number2413739-88-3
Groups experimental
ATC Codes nan
DescriptionEvifacotrep is a small molecule drug. The usage of the INN stem '-cotrep' in the name indicates that Evifacotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist. Evifacotrep has a monoisotopic molecular weight of 441.06 Da.

Cross-references: BindingDB: 50647393 CHEMBL4752870
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9UL62 TRPC5 Homo sapiens Human PF00023 PF12796 PF00520 PF08344 8.1 IC50 ChEMBL
Q9UBN4 TRPC4 Homo sapiens Human PF00023 PF12796 PF00520 PF08344 7.8 IC50 ChEMBL