Molecule Details
InChIKeyIPTSYCYNQJITNJ-UHFFFAOYSA-N
Compound Name6-methyl-N-(4-methyl-2-pyridinyl)-2-phenylpyrimidin-4-amine
Canonical SMILESCc1ccnc(Nc2cc(C)nc(-c3ccccc3)n2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL6.42
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.2 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.5 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.4 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 6.3 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q16620 NTRK2 Homo sapiens Human PF07679 PF13855 PF16920 PF01462 PF07714 6.3 Ki ChEMBL
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 6.2 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.0 Ki ChEMBL