Molecule Details
InChIKeyIPKHSYHXXAIZDD-UHFFFAOYSA-N
Compound Name1-(1H-indol-3-yl)-3-[(5-thieno[3,2-c]pyridin-2-yl-3-pyridinyl)oxy]propan-2-amine
Canonical SMILESNC(COc1cncc(-c2cc3cnccc3s2)c1)Cc1c[nH]c2ccccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)18
Pfam Stratification Cross-Family
Avg pChEMBL6.66
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (18)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13627 DYRK1A Homo sapiens Human PF00069 7.5 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 7.2 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.2 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.1 Ki ChEMBL
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 6.9 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.7 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.7 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.7 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 6.7 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.6 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.5 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.4 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.4 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.2 Ki ChEMBL
Q05513 PRKCZ Homo sapiens Human PF00130 PF00564 PF00069 PF00433 6.0 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.0 Ki ChEMBL