Molecule Details
InChIKeyIPEXHQGMTHOKQV-UHFFFAOYSA-N
Compound NameSar-407899
Canonical SMILESO=c1[nH]ccc2cc(OC3CCNCC3)ccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL7.79
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 8.4 Kd ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 8.1 Kd ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 8.0 Kd ChEMBL
Q2M2I8 AAK1 Homo sapiens Human PF00069 7.9 Kd ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.9 Kd ChEMBL
Q6ZSR9 Homo sapiens Human PF15282 7.9 Kd ChEMBL
Q9NSY1 BMP2K Homo sapiens Human PF15282 PF00069 7.9 Kd ChEMBL
Q9Y5S2 CDC42BPB Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 7.8 Kd ChEMBL
Q16512 PKN1 Homo sapiens Human PF02185 PF00069 PF00433 7.7 Kd ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 7.7 Kd ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.4 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.7 IC50 ChEMBL;BindingDB