Molecule Details
| InChIKey | INGXCNVWWKKWOO-LJQANCHMSA-N |
|---|---|
| Compound Name | Opc 51803 |
| Canonical SMILES | CC(C)NC(=O)C[C@H]1CCCN(C(=O)c2ccc(N3CCCC3)cc2Cl)c2ccccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.42 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB05838 |
|---|---|
| Drug Name | OPC-51803 |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | OPC-51803 is the first nonpeptide vasopressin (AVP) V(2)-receptor-selective agonist. It is a V(2)-selective agonist that produces a significant antidiuretic action after single and multiple oral dosing in AVP-deficient and normal AVP states. It is useful therapeutic drug in the treatment of hypothal... |
Categories: Heterocyclic Compounds, Fused-Ring Receptors, Vasopressin, agonists
Cross-references: BindingDB: 50117486 CHEMBL332447 ChemSpider: 2302070 PubChem:3038506 PubChem:175427043 ZINC: ZINC000003828536
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P30518 | AVPR2 | Vasopressin V2 receptor | agonist | targets |