InChIKey	INDBQLZJXZLFIT-UHFFFAOYSA-N
Compound Name	Primaquine
Canonical SMILES	COc1cc(NC(C)CCCN)c2ncccc2c1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	7.35
Source	BindingDB;ChEMBL

DrugBank ID	DB01087
Drug Name	Primaquine
CAS Number	90-34-6
Groups	approved investigational
ATC Codes	P01BA03
Description	An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introdu...

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Categories: Aminoquinolines Anti-Infective Agents Antibiotics for Pneumocystis Pneumonia Antimalarials Antiparasitic Agents Antiparasitic Products, Insecticides and Repellents Antiprotozoals Cytochrome P-450 CYP1A2 Inducers Cytochrome P-450 CYP1A2 Inducers (strength unknown) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (moderate) Cytochrome P-450 CYP2D6 Inhibitors (weak) Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (moderate) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Heterocyclic Compounds, Fused-Ring Methemoglobinemia Associated Agents Moderate Risk QTc-Prolonging Agents P-glycoprotein inhibitors QTc Prolonging Agents Quinolines

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Cross-references: BindingDB: 71542 ChEBI: 8405 CHEMBL506 ChemSpider: 4739 Drugs Product Database (DPD): 3336 C07627 PharmGKB: PA451103 PubChem:4908 PubChem:46508222 RxCUI: 8687 Therapeutic Targets Database: DAP000216 Wikipedia: Primaquine