Molecule Details
| InChIKey | IMYHGORQCPYVBZ-NLFFAJNJSA-N |
|---|---|
| Compound Name | 3-Methyl-1-phenethyl-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester |
| Canonical SMILES | CCC(=O)N(c1ccccc1)[C@@]1(C(=O)OC)CCN(CCc2ccccc2)C[C@H]1C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.58 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB09174 |
|---|---|
| Drug Name | Lofentanil |
| CAS Number | 61380-40-3 |
| Groups | experimental illicit |
| ATC Codes | nan |
| Description | Lofentanil is an analog of fentanyl and is one of the most potent opioids available today. It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly more potent than this drug. |
Categories: Analgesics Central Nervous System Agents Central Nervous System Depressants Narcotics Opioids Peripheral Nervous System Agents Piperidines Sensory System Agents Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
Cross-references: BindingDB: 50027473 CHEMBL28198 ChemSpider: 8245580 PDB: EID PubChem:10070040 PubChem:310265083 Wikipedia: Lofentanil ZINC: ZINC000004216763