Molecule Details
| InChIKey | IMNAMBYRWSGKHX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[[1-[5-Chloro-4-(trifluoromethyl)pyridin-2-yl]-3-methylazetidin-3-yl]methoxy]-5-cyclopropyl-2-fluorobenzamide |
| Canonical SMILES | CC1(COc2cc(F)c(C(N)=O)cc2C2CC2)CN(c2cc(C(F)(F)F)c(Cl)cn2)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.82 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15858 | SCN9A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 8.3 | IC50 | ChEMBL;BindingDB |
| P35498 | SCN1A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 8.2 | IC50 | BindingDB |
| Q14524 | SCN5A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 7.0 | IC50 | BindingDB |