N-(1-(3-amino-3-oxopropyl)-5-(N-methylcyclohexanecarboxamido)-1H-benzo[d]imidazol-2-yl)-4-cyanobenzamide

InChIKey	`IMLXFZLHOPEBPM-UHFFFAOYSA-N`
Compound Name	N-(1-(3-amino-3-oxopropyl)-5-(N-methylcyclohexanecarboxamido)-1H-benzo[d]imidazol-2-yl)-4-cyanobenzamide
Canonical SMILES	`CN(C(=O)C1CCCCC1)c1ccc2c(c1)nc(NC(=O)c1ccc(C#N)cc1)n2CCC(N)=O`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	12
Pfam Stratification	Cross-Family
Avg pChEMBL	6.58
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q08881	ITK	Homo sapiens	Human	PF00779 PF00169 PF07714 PF00017 PF00018	8.4	IC50	ChEMBL;BindingDB
O96017	CHEK2	Homo sapiens	Human	PF00498 PF00069	7.7	Ki	ChEMBL
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	7.3	Ki	ChEMBL
P48730	CSNK1D	Homo sapiens	Human	PF00069	6.4	Ki	ChEMBL
Q9NWZ3	IRAK4	Homo sapiens	Human	PF07714	6.4	Ki	ChEMBL
P22607	FGFR3	Homo sapiens	Human	PF21165 PF07679 PF13927 PF07714	6.3	Ki	ChEMBL
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	6.3	Ki	ChEMBL
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	6.1	Ki	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	6.0	Ki	ChEMBL
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	6.0	Ki	ChEMBL
P51812	RPS6KA3	Homo sapiens	Human	PF00069 PF00433	6.0	Ki	ChEMBL