8-[3-chloro-5-(1-methylindazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one

InChIKey	`IMJBJHNFFBDGFG-UHFFFAOYSA-N`
Compound Name	8-[3-chloro-5-(1-methylindazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one
Canonical SMILES	`Cn1ncc2cc(-c3cnc4[nH]cc(Cl)c4c3N3CCC4(CCNC4=O)CC3)ccc21`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.47
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P24863	CCNC	Homo sapiens	Human	PF16899 PF00134	8.7	IC50	ChEMBL;BindingDB
P49336	CDK8	Homo sapiens	Human	PF00069	8.7	IC50	ChEMBL
Q9BWU1	CDK19	Homo sapiens	Human	PF00069	8.0	IC50	ChEMBL;BindingDB