Molecule Details
InChIKeyILZHUXOVLLTBFC-REWPJTCUSA-N
Compound Name1-{2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl}-3-tert-butyl-thiourea
Canonical SMILESCc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C/N=C(/S)NC(C)(C)C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.55
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P41143 OPRD1 Homo sapiens Human PF00001 9.7 IC50 ChEMBL;BindingDB
P41145 OPRK1 Homo sapiens Human PF00001 8.6 IC50 ChEMBL;BindingDB
P35372 OPRM1 Homo sapiens Human PF00001 7.4 IC50 ChEMBL;BindingDB