Molecule Details
InChIKeyILUGAYBMBIJXHC-UHFFFAOYSA-N
Compound NameN-[3-[5-[2-[5-[(dimethylamino)methyl]-2-methoxyanilino]pyrimidin-4-yl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]-2-phenylacetamide
Canonical SMILESCOc1ccc(CN(C)C)cc1Nc1nccc(-c2c(-c3cccc(NC(=O)Cc4ccccc4)c3)nc3sccn23)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.7
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 7.6 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 7.3 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 7.0 Ki ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.6 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.4 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.3 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.2 Ki ChEMBL