Molecule Details
| InChIKey | ILKDWZKZLIHMFM-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-Tert-Butyl-3-Naphthalen-2-Yl-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine |
| Canonical SMILES | CC(C)(C)n1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 8 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.08 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (8)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P12931 | SRC | Homo sapiens | Human | PF07714 PF00017 PF00018 | 6.9 | IC50 | ChEMBL;BindingDB |
| O14939 | PLD2 | Homo sapiens | Human | PF00614 PF13091 PF00787 | 6.8 | IC50 | BindingDB |
| P78527 | PRKDC | Homo sapiens | Human | PF20500 PF20502 PF08163 PF19704 PF02259 PF02260 PF00454 | 6.4 | IC50 | ChEMBL |
| Q13393 | PLD1 | Homo sapiens | Human | PF00169 PF00614 PF13091 PF00787 | 6.3 | IC50 | BindingDB |
| Q8MMZ7 | PKG | Toxoplasma gondii | Pathogen | PF00027 PF00069 | 7.8 | IC50 | BindingDB |
| Q9BJF5 | CDPK1 | Toxoplasma gondii | Pathogen | PF13499 PF00069 | 7.8 | IC50 | ChEMBL;BindingDB |
| A0A7S7LIM2 | Cryptosporidium parvum | Pathogen | PF13499 PF00069 | 7.8 | IC50 | BindingDB | |
| Q8IBS5 | CDPK4 | Plasmodium falciparum (isolate 3D7) | Pathogen | PF13499 PF00069 | 6.8 | IC50 | ChEMBL;BindingDB |