Molecule Details
| InChIKey | ILJURMUTUMKSGV-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[6-(2,4-Difluoro-phenyl)-pyridazin-4-yl]-benzonitrile |
| Canonical SMILES | N#Cc1cccc(-c2cnnc(-c3ccc(F)cc3F)c2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.7 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P31644 | GABRA5 | Homo sapiens | Human | PF02931 PF02932 | 7.8 | Ki | ChEMBL;BindingDB |
| P18507 | GABRG2 | Homo sapiens | Human | PF02931 PF02932 | 7.7 | Ki | ChEMBL |
| P28472 | GABRB3 | Homo sapiens | Human | PF02931 PF02932 | 7.7 | Ki | ChEMBL |
| P34903 | GABRA3 | Homo sapiens | Human | PF02931 PF02932 | 7.6 | Ki | ChEMBL;BindingDB |