Molecule Details
InChIKeyIJRBJCMLWLFMIN-UHFFFAOYSA-N
Compound Name1-[3-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]ethanone
Canonical SMILESCC(=O)c1cccc(-c2cnc3[nH]ccc3c2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)17
Pfam Stratification Cross-Family
Avg pChEMBL6.33
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (17)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 7.0 Ki ChEMBL
P16591 FER Homo sapiens Human PF00611 PF07714 PF00017 6.9 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 6.8 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 6.5 IC50 ChEMBL
P07332 FES Homo sapiens Human PF00611 PF07714 PF00017 6.4 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.3 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.2 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 6.2 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.2 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.1 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
P43405 SYK Homo sapiens Human PF07714 PF00017 6.1 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.1 Ki ChEMBL