4-(1H-indol-3-yl)-N-[(3R,5S)-5-([1,2,4]triazolo[4,3-a]pyridin-3-yl)piperidin-3-yl]-5-(trifluoromethyl)pyrimidin-2-amine

InChIKey	`IJQBKJGUIDXXLI-LSDHHAIUSA-N`
Compound Name	4-(1H-indol-3-yl)-N-[(3R,5S)-5-([1,2,4]triazolo[4,3-a]pyridin-3-yl)piperidin-3-yl]-5-(trifluoromethyl)pyrimidin-2-amine
Canonical SMILES	`FC(F)(F)c1cnc(N[C@H]2CNC[C@@H](c3nnc4ccccn34)C2)nc1-c1c[nH]c2ccccc12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	6.7
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O75909	CCNK	Homo sapiens	Human	PF00134 PF21797	6.7	IC50	ChEMBL
P50613	CDK7	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL
P51946	CCNH	Homo sapiens	Human	PF16899 PF00134	6.7	IC50	ChEMBL
P51948	MNAT1	Homo sapiens	Human	PF25811 PF06391 PF17121	6.7	IC50	ChEMBL
Q9NYV4	CDK12	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL