Molecule Details
| InChIKey | IJMBOKOTALXLKS-UHFFFAOYSA-N |
|---|---|
| Compound Name | Molidustat |
| Canonical SMILES | O=c1c(-n2ccnn2)c[nH]n1-c1cc(N2CCOCC2)ncn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.41 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB15642 |
|---|---|
| Drug Name | Molidustat |
| CAS Number | 1154028-82-6 |
| Groups | investigational |
| ATC Codes | B03XA09 |
| Description | Molidustat is under investigation in clinical trial NCT03350321 (A Study of Molidustat for Correction of Renal Anemia in Non-dialysis Subjects). |
Categories: Antianemic Preparations Blood and Blood Forming Organs
Cross-references: BindingDB: 118339 CHEMBL3646118 ChemSpider: 30922476 PDB: A1H RxCUI: 2637535 Wikipedia: Molidustat ZINC: ZINC000167006010
Target Activities (3)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| Q96KS0 | EGLN2 | Prolyl hydroxylase EGLN2 | inhibitor | targets |