3-(4-(ethylsulfonylmethyl)bicyclo[2.2.2]octan-1-yl)-4-methyl-5-(2-(trifluoromethyl)phenyl)-4H-1,2,4-triazole

InChIKey	`IIUAOVVCEISVLV-UHFFFAOYSA-N`
Compound Name	3-(4-(ethylsulfonylmethyl)bicyclo[2.2.2]octan-1-yl)-4-methyl-5-(2-(trifluoromethyl)phenyl)-4H-1,2,4-triazole
Canonical SMILES	`CCS(=O)(=O)CC12CCC(c3nnc(-c4ccccc4C(F)(F)F)n3C)(CC1)CC2`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.55
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P28845	HSD11B1	Homo sapiens	Human	PF00106	7.6	IC50	ChEMBL;BindingDB
P80365	HSD11B2	Homo sapiens	Human	PF00106	7.5	IC50	ChEMBL;BindingDB