Molecule Details
InChIKeyIIRWNGPLJQXWFJ-KRWDZBQOSA-N
Compound NameAt-13148
Canonical SMILESNC[C@@](O)(c1ccc(Cl)cc1)c1ccc(-c2cn[nH]c2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)21
Pfam Stratification Homologous
Avg pChEMBL7.6
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (21)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 8.1 Kd ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 7.9 IC50 ChEMBL
O75676 RPS6KA4 Homo sapiens Human PF00069 PF00433 7.9 IC50 ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 7.9 IC50 ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 7.9 IC50 ChEMBL
Q15349 RPS6KA2 Homo sapiens Human PF00069 PF00433 7.9 IC50 ChEMBL
Q9UBS0 RPS6KB2 Homo sapiens Human PF00069 PF00433 7.9 IC50 ChEMBL
Q9UK32 RPS6KA6 Homo sapiens Human PF00069 PF00433 7.9 IC50 ChEMBL
P22694 PRKACB Homo sapiens Human PF00069 7.8 Kd ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.8 Kd ChEMBL
Q16512 PKN1 Homo sapiens Human PF02185 PF00069 PF00433 7.6 Kd ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.6 Kd ChEMBL
O95835 LATS1 Homo sapiens Human PF00069 PF00433 PF00627 7.6 Kd ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.6 Kd ChEMBL
Q15418 RPS6KA1 Homo sapiens Human PF00069 PF00433 7.5 IC50 ChEMBL
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 7.4 IC50 ChEMBL;BindingDB
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 7.4 Kd ChEMBL
Q96BR1 SGK3 Homo sapiens Human PF00069 PF00433 PF00787 7.3 IC50 ChEMBL
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 7.3 IC50 ChEMBL;BindingDB
P25098 GRK2 Homo sapiens Human PF00169 PF00069 PF00615 6.8 Kd ChEMBL
P31751 AKT2 Homo sapiens Human PF00169 PF00069 PF00433 6.4 IC50 ChEMBL;BindingDB