Molecule Details
| InChIKey | IILNBGZKSQQREW-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[2-(4-fluorophenyl)-8-methylimidazo[1,2-a]pyrazin-3-yl]-N-(3-methoxy-2,2-dimethylpropyl)pyrimidin-2-amine |
| Canonical SMILES | COCC(C)(C)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3c(C)nccn23)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.65 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P48730 | CSNK1D | Homo sapiens | Human | PF00069 | 7.7 | Ki | ChEMBL |
| P45984 | MAPK9 | Homo sapiens | Human | PF00069 | 7.6 | Ki | ChEMBL |
| P45983 | MAPK8 | Homo sapiens | Human | PF00069 | 6.3 | Ki | ChEMBL |
| O94806 | PRKD3 | Homo sapiens | Human | PF00130 PF00169 PF00069 PF25525 | 6.2 | Ki | ChEMBL |
| P48729 | CSNK1A1 | Homo sapiens | Human | PF00069 | 6.1 | Ki | ChEMBL |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 6.0 | Ki | ChEMBL |