Molecule Details
| InChIKey | IFSNOUHZJMGMOD-UHFFFAOYSA-N |
|---|---|
| Compound Name | US11160797, Example 48 |
| Canonical SMILES | CC(C)n1cc(-c2cncc(-c3ccc4c(c3)CS(=O)(=O)N4C)c2)ccc1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.61 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q04771 | ACVR1 | Homo sapiens | Human | PF01064 PF07714 PF08515 | 7.2 | IC50 | ChEMBL;BindingDB |
| P37023 | ACVRL1 | Homo sapiens | Human | PF07714 PF08515 | 6.7 | IC50 | ChEMBL;BindingDB |
| P36894 | BMPR1A | Homo sapiens | Human | PF01064 PF07714 PF08515 | 6.5 | IC50 | ChEMBL;BindingDB |
| O00238 | BMPR1B | Homo sapiens | Human | PF01064 PF07714 PF08515 | 6.0 | IC50 | ChEMBL;BindingDB |