Molecule Details
InChIKeyIFQICUARAXVEIQ-UHFFFAOYSA-N
Compound Name3-Iodo-6,11-dihydropyridazino[3,4-b][1,5]benzodiazepin-5-one
Canonical SMILESO=C1Nc2ccccc2Nc2nnc(I)cc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)18
Pfam Stratification Cross-Family
Avg pChEMBL6.51
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (18)
Target Gene Organism Category Pfam pChEMBL Type Source
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 7.1 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.1 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.9 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.8 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P22607 FGFR3 Homo sapiens Human PF21165 PF07679 PF13927 PF07714 6.4 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.4 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.3 Ki ChEMBL
P16591 FER Homo sapiens Human PF00611 PF07714 PF00017 6.3 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.1 Ki ChEMBL
P43405 SYK Homo sapiens Human PF07714 PF00017 6.1 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.1 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL