Molecule Details
| InChIKey | IFKLAQQSCNILHL-QHAWAJNXSA-N |
|---|---|
| Compound Name | Butorphanol |
| Canonical SMILES | Oc1ccc2c(c1)[C@@]13CCCC[C@@]1(O)[C@@H](C2)N(CC1CCC1)CC3 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.17 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB00611 |
|---|---|
| Drug Name | Butorphanol |
| CAS Number | 42408-82-2 |
| Groups | approved illicit investigational vet_approved |
| ATC Codes | N02AF01 |
| Description | A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain. |
Categories: Alkaloids Analgesics Antitussive Agents Central Nervous System Agents Central Nervous System Depressants Heterocyclic Compounds, Fused-Ring Mixed Agonist / Antagonist Opioids Morphinan Derivatives Morphinans Narcotics Nervous System Opiate Alkaloids Opiate Partial Agonists Opioid Agonist/Antagonist Opioid Antagonists Opioids Peripheral Nervous System Agents Phenanthrenes Respiratory System Agents Sensory System Agents Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
Cross-references: BindingDB: 50240437 ChEBI: 3242 CHEMBL33986 ChemSpider: 16735714 Drugs Product Database (DPD): 11238 C06863 D00837 PharmGKB: PA164745398 PubChem:6916249 PubChem:46507553 RxCUI: 1841 Therapeutic Targets Database: DAP000214 Wikipedia: Butorphanol ZINC: ZINC000003812988