Molecule Details
| InChIKey | IELDEMOVCFANHT-UHFFFAOYSA-N |
|---|---|
| Compound Name | Thrombin inhibitor 6 |
| Canonical SMILES | CC(C)(C)C(=O)n1nc(-c2ccc[nH]c2=O)cc1NCc1ccc(Cl)s1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.94 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00734 | F2 | Homo sapiens | Human | PF00594 PF00051 PF09396 PF00089 | 9.0 | IC50 | ChEMBL |
| P17538 | CTRB1 | Homo sapiens | Human | PF00089 | 6.4 | IC50 | ChEMBL |
| P40313 | CTRL | Homo sapiens | Human | PF00089 | 6.4 | IC50 | ChEMBL |
| Q6GPI1 | CTRB2 | Homo sapiens | Human | PF00089 | 6.4 | IC50 | ChEMBL |
| Q99895 | CTRC | Homo sapiens | Human | PF00089 | 6.4 | IC50 | ChEMBL |