Molecule Details
InChIKeyIEFFSHLHNYVSEF-UHFFFAOYSA-N
Compound NameClk-IN-T3
Canonical SMILESCN1CCN(C(=O)C(C)(C)c2ccc(C(=O)Nc3cn4cc(-c5ccncc5)ccc4n3)cc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.44
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P49759 CLK1 Homo sapiens Human PF00069 9.2 IC50 ChEMBL;BindingDB
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.7 IC50 ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 7.8 IC50 ChEMBL;BindingDB
P49761 CLK3 Homo sapiens Human PF00069 7.0 IC50 ChEMBL
Q9H0K1 SIK2 Homo sapiens Human PF00069 PF23312 6.9 IC50 ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.9 IC50 ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.6 IC50 ChEMBL;BindingDB
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.5 IC50 ChEMBL