Molecule Details
InChIKeyIEDDDZFQZKDRBJ-UHFFFAOYSA-N
Compound NameAplithianine A
Canonical SMILESCn1cncc1C1=CN(c2ncnc3[nH]cnc23)CCS1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Homologous
Avg pChEMBL7.28
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 7.9 IC50 ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 7.5 IC50 ChEMBL
Q9UEW8 STK39 Homo sapiens Human PF12202 PF00069 7.5 IC50 ChEMBL
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 7.4 IC50 ChEMBL
O95835 LATS1 Homo sapiens Human PF00069 PF00433 PF00627 7.2 IC50 ChEMBL
P49759 CLK1 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
Q9NRM7 LATS2 Homo sapiens Human PF00069 PF00433 7.2 IC50 ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.5 IC50 ChEMBL