Molecule Details
InChIKeyIBUMAHMUIWPTCV-AWNIVKPZSA-N
Compound Name(E)-2-cyano-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide
Canonical SMILESCOc1cc(-c2n[nH]c3ccc(/C=C(\C#N)C(N)=O)cc23)cc(OC)c1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL6.92
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 7.8 IC50 BindingDB
P51955 NEK2 Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB
P53350 PLK1 Homo sapiens Human PF00069 PF00659 6.2 IC50 ChEMBL;BindingDB