Molecule Details
InChIKeyIBPSHHSPUPWXHN-UHFFFAOYSA-N
Compound NameN-[2-(dimethylamino)-5-[5-[2-(3-morpholin-4-ylanilino)pyrimidin-4-yl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]benzamide
Canonical SMILESCN(C)c1ccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)cc1NC(=O)c1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.5
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 7.5 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.6 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.5 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.4 Ki ChEMBL
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 6.0 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL