Molecule Details
| InChIKey | IAPZXUKYTCQQFE-QZKDJMESSA-N |
|---|---|
| Compound Name | (2R,3R,3aS,5S)-2-(6-aminopurin-9-yl)-5-[carboxy(hydroxy)methyl]-3-hydroxy-3,3a-dihydro-2H-furo[3,2-b]furan-5-carboxylic acid |
| Canonical SMILES | Nc1ncnc2c1ncn2[C@@H]1OC2=C[C@@](C(=O)O)(C(O)C(=O)O)O[C@H]2[C@H]1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.8 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 6.8 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 6.8 | IC50 | ChEMBL |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 6.8 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 6.8 | IC50 | ChEMBL |
| Q13370 | PDE3B | Homo sapiens | Human | PF00233 | 6.8 | IC50 | ChEMBL |
| Q14432 | PDE3A | Homo sapiens | Human | PF00233 | 6.8 | IC50 | ChEMBL |