Molecule Details
InChIKeyIALDYVNFZAPNJV-UHFFFAOYSA-N
Compound Name6-[7-methoxy-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-N-pyrrolidin-3-ylpyridin-2-amine
Canonical SMILESCOc1cc2ncc(-c3cccc(NC4CCNC4)n3)n2cc1-c1cnn(C)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL8.93
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96GD4 AURKB Homo sapiens Human PF00069 10.9 Kd ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 9.5 Kd ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 9.2 IC50 ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 9.2 IC50 ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 9.1 IC50 ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 9.0 IC50 ChEMBL
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 9.0 IC50 ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 8.3 IC50 ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 8.3 IC50 ChEMBL
Q08345 DDR1 Homo sapiens Human PF21114 PF00754 PF07714 8.1 IC50 ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 7.7 IC50 ChEMBL