Molecule Details
InChIKeyHZZNUWNFLHMBRW-AWEZNQCLSA-N
Compound Name5-ethyl-4-(1H-indol-3-yl)-N-[(3S)-piperidin-3-yl]pyrimidin-2-amine
Canonical SMILESCCc1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2ccccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.12
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P51946 CCNH Homo sapiens Human PF16899 PF00134 9.4 Kd ChEMBL;BindingDB
P50613 CDK7 Homo sapiens Human PF00069 8.6 IC50 ChEMBL
P51948 MNAT1 Homo sapiens Human PF25811 PF06391 PF17121 7.7 IC50 ChEMBL
Q9NYV4 CDK12 Homo sapiens Human PF00069 6.9 IC50 ChEMBL;BindingDB
O75909 CCNK Homo sapiens Human PF00134 PF21797 6.8 IC50 ChEMBL
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 6.4 IC50 ChEMBL;BindingDB
P50750 CDK9 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 6.0 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.0 IC50 ChEMBL;BindingDB