N-[2-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrrolo[2,1-f][1,2,4]triazin-7-yl]phenyl]-N-methylmethanesulfonamide

InChIKey	`HZUPDOJVKYRRMY-UHFFFAOYSA-N`
Compound Name	N-[2-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrrolo[2,1-f][1,2,4]triazin-7-yl]phenyl]-N-methylmethanesulfonamide
Canonical SMILES	`COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.7
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UM73	ALK	Homo sapiens	Human	PF12810 PF00629 PF07714	7.4	IC50	ChEMBL;BindingDB
P06748	NPM1	Homo sapiens	Human	PF16276 PF03066	6.7	IC50	ChEMBL
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	6.0	IC50	ChEMBL;BindingDB