Molecule Details
InChIKeyHZRJHVDNTDBTOZ-QGZVFWFLSA-N
Compound NameBay-985
Canonical SMILESC[C@H](c1ccnc(Nc2nc3ccc(-c4cc(N(C)C)ncn4)cc3[nH]2)c1)N1CCN(C(=O)CC(F)(F)F)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.04
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q14164 IKBKE Homo sapiens Human PF00069 PF18394 PF18396 8.7 IC50 ChEMBL;BindingDB
Q56UN5 MAP3K19 Homo sapiens Human PF00069 8.0 Kd ChEMBL
Q9UHD2 TBK1 Homo sapiens Human PF00069 PF18394 PF18396 7.5 IC50 ChEMBL;BindingDB
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.9 IC50 ChEMBL;BindingDB
Q9UK32 RPS6KA6 Homo sapiens Human PF00069 PF00433 6.6 IC50 ChEMBL;BindingDB
Q9UEE5 STK17A Homo sapiens Human PF00069 6.5 IC50 ChEMBL;BindingDB
P10632 CYP2C8 Homo sapiens Human PF00067 6.1 IC50 ChEMBL;BindingDB
Q13163 MAP2K5 Homo sapiens Human PF00564 PF00069 6.1 IC50 ChEMBL