InChIKey	HYWYRSMBCFDLJT-UHFFFAOYSA-N
Compound Name	Nimesulide
Canonical SMILES	CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1Oc1ccccc1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	6.57
Source	BindingDB;ChEMBL

DrugBank ID	DB04743
Drug Name	Nimesulide
CAS Number	51803-78-2
Groups	approved withdrawn
ATC Codes	M01AX17 M02AA26
Description	Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years...

---

Categories: Agents causing hyperkalemia Agents that produce hypertension Amides Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Antiarrhythmic agents Antiinflammatory Preparations, Non-Steroids for Topical Use Antiinflammatory and Antirheumatic Products Antiinflammatory and Antirheumatic Products, Non-Steroids Antiplatelet agents Antirheumatic Agents Bradycardia-Causing Agents Calcium Channel Blockers Cyclooxygenase Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates Enzyme Inhibitors Musculo-Skeletal System Nephrotoxic agents Peripheral Nervous System Agents Selective Cyclooxygenase 2 Inhibitors (NSAIDs) Sensory System Agents Sulfones Sulfur Compounds Topical Products for Joint and Muscular Pain

---

Cross-references: BindingDB: 50056999 ChEBI: 44445 CHEMBL56367 ChemSpider: 4339 D01049 PDB: NIM PharmGKB: PA137179528 PubChem:4495 PubChem:46507721 RxCUI: 53694 Therapeutic Targets Database: DPR000079 Wikipedia: Nimesulide ZINC: ZINC000004617749