Molecule Details
InChIKeyHXNUFFCHRIWTRZ-UHFFFAOYSA-N
Compound NameSR-318
Canonical SMILESNc1c(C(=O)NCc2ccc(C(=O)NCCCC3CCCCC3)cc2)cnn1-c1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL6.89
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16539 MAPK14 Homo sapiens Human PF00069 8.3 IC50 ChEMBL;BindingDB
Q15759 MAPK11 Homo sapiens Human PF00069 7.5 IC50 ChEMBL;BindingDB
P01375 TNF Homo sapiens Human PF00229 6.5 IC50 ChEMBL
Q9NYL2 MAP3K20 Homo sapiens Human PF07714 PF07647 6.0 IC50 ChEMBL
Q9Y2U5 MAP3K2 Homo sapiens Human PF00564 PF00069 6.0 IC50 ChEMBL;BindingDB