Molecule Details
| InChIKey | HXJKWPGVENNMCC-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2,5-Dimethoxy-4-ethylamphetamine |
| Canonical SMILES | CCc1cc(OC)c(CC(C)N)cc1OC |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.23 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB01467 |
|---|---|
| Drug Name | 2,5-Dimethoxy-4-ethylamphetamine |
| CAS Number | 22004-32-6 |
| Groups | experimental illicit |
| ATC Codes | nan |
| Description | nan |
Categories: Agents producing tachycardia Agents that produce hypertension Amines Amphetamines Ethylamines Phenethylamines Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Sympathomimetics
Cross-references: BindingDB: 81965 ChEBI: 191249 CHEMBL8224 ChemSpider: 25499 PubChem:27402 PubChem:46504746 Wikipedia: 2,5-Dimethoxy-4-ethylamphetamine
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 7.8 | Ki | BindingDB |
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 7.6 | Ki | BindingDB |
| P41595 | HTR2B | Homo sapiens | Human | PF00001 | 7.5 | Ki | BindingDB |
| P28335 | HTR2C | Homo sapiens | Human | PF00001 | 7.0 | Ki | BindingDB |
| P18089 | ADRA2B | Homo sapiens | Human | PF00001 | 6.2 | Ki | BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P28223 | HTR2A | 5-hydroxytryptamine receptor 2A | inhibitor | targets |