Molecule Details
InChIKeyHXCNRYXBZNHDNE-UHFFFAOYSA-N
Compound NamePirenperone
Canonical SMILESCc1nc2ccccn2c(=O)c1CCN1CCC(C(=O)c2ccc(F)cc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Homologous
Avg pChEMBL7.9
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21405
Drug NamePirenperone
CAS Number75444-65-4
Groups experimental
ATC Codes nan
DescriptionPirenperone is a small molecule drug. The usage of the INN stem '-perone' in the name indicates that Pirenperone is a tranquillizer, neuroleptic, 4'-fluoro-4-piperidinobutyrophenone derivative. Pirenperone has a monoisotopic molecular weight of 393.19 Da.

Categories: Central Nervous System Agents Central Nervous System Depressants Psychotropic Drugs Tranquilizing Agents
Cross-references: BindingDB: 50024205 ChEBI: 92444 CHEMBL18331 ZINC: ZINC000000538194
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P28223 HTR2A Homo sapiens Human PF00001 9.0 Ki BindingDB
P34969 HTR7 Homo sapiens Human PF00001 8.2 Ki BindingDB
P28335 HTR2C Homo sapiens Human PF00001 7.2 Ki ChEMBL;BindingDB
P41595 HTR2B Homo sapiens Human PF00001 7.2 Ki BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P34969 HTR7 5-hydroxytryptamine receptor 7 antagonist targets