Molecule Details
| InChIKey | HWJPWWYTGBZDEG-AWEZNQCLSA-N |
|---|---|
| Compound Name | 5-{[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl}pyrimidine-2,4-diamine |
| Canonical SMILES | COc1cc(Cc2cnc(N)nc2N)c2c(c1OC)O[C@H](C1CC1)C=C2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.36 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB08741 |
|---|---|
| Drug Name | 5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 50336513 ChEBI: 131752 CHEMBL1236788 ChemSpider: 8423047 PDB: XCF PubChem:10247560 PubChem:99445212 ZINC: ZINC000003612862
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P0A017 | folA | Dihydrofolate reductase | binder | targets |